Trenbolone
Trenbolone
is a steroid used on livestock to increase muscle growth and appetite.
To increase its effective half-life, trenbolone is not used in a refined
form, but is rather administered as ester derivatives such as trenbolone acetate, trenbolone enanthate, or trenbolone cyclohexylmethylcarbonate (Parabolan). Plasma lipases then cleave the ester group in the bloodstream leaving free trenbolone.
Bodybuilders and athletes have been known to use the drug illicitly because they experience an increase in body mass more effectively than by weight training
alone and because of its reputation as a fat-burning, as well as
bulking agent. In the United States, possession or use of trenbolone for
humans is a violation of federal law. The DEA classifies trenbolone as a
schedule III drug.Trenbolone is classified as a Schedule 4 drug in Canada and a class C drug with no penalty for personal use or possession in the United Kingdom.Use or possession of steroids without a prescription is a crime in Australia.It is, nonetheless, available over the counter in many countries and fully legal for use.
Use and effects
Trenbolone compounds have a binding affinity for the androgen receptor five times as high as that of testosterone. Once metabolized, the drugs have the effect of increasing ammonium ion uptake by muscles, leading to an increase in the rate of protein synthesis. It may also have the secondary effects of stimulating appetite and decreasing the rate of catabolism, as all anabolic steroids are believed to; however, catabolism likely increases significantly once the steroid is no longer taken.Trenbolone has proven popular with anabolic steroid users, as some believe it is not metabolized by aromatase or 5α-reductase into estrogenic compounds such as estradiol, or into dihydrotestosterone; however, studies on this are mixed, with some studies showing a potential increase in both.At least one study in rats has shown trenbolone to cause gene expression with the androgen receptor at least as potent as DHT. This evidence tends to indicate Trenbolone can cause an increase in male secondary sex characteristics without the need to convert to dihydrotestosterone.
Since steroids generally cause virilization effects in women in even small doses, this drug should not be taken by women. Kidney toxicity has been suggested, but has not yet been proven, and scientific evidence supporting the idea is absent from the bodybuilding community that perpetuates this idea. The origin of this myth most likely has to do with the rust-colored oxidized metabolites of trenbolone which are excreted in urine and often mistaken for blood.Trenbolone and 17epi-trenbolone are both excreted in urine as conjugates that can be hydrolyzed with beta-glucuronidase. This implies that trenbolone leaves the body as beta-glucuronides or sulfates.
As with most other drugs the side effects are dose dependent, and can include the following:
- Dramatic increases in strength, sex drive, heart rate and blood pressure.
- Heavy breathing (feeling of breathlessness).
- Elevated body temperature and night sweats.
- Production of dark colored urine.
- Insomnia and nightmares.
- Erectile dysfunction.
- Reduction in appetite.
- Paranoia.
- Enuresis.
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Parabolin Trenbolone 5x ampule (76.5 mg/1.5 ml) is an injectable steroid. It affects protein digestion in an effective manner. Use of this steroid advances the strength and size in the users.
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